Maple Leaf to Prevent Wrinkles: The New ‘Botox’ Without Injections

Scientists have used extract from maple leaf to create a skincare product that may soon prevent wrinkles in the same way that Botox does, but without injections that goes with Botox.

According to the new research, maple leaf extract could be used to prevent wrinkles. The study was presented at the 256th National Meeting & Exposition of the American Chemical Society. The senior researcher of the study is Prof. Navindra P. Seeram, of the Department of Biomedical and Pharmaceutical Sciences at the University of Rhode Island in Kingston.

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Prof. Seeram and his team studied the therapeutic properties of maple leaves. “Native Americans used leaves from red maple trees in their traditional system of medicine.”

Rigorous scientific studies have supported the health benefits of products gotten from maple trees. Three years ago at the 253rd annual meeting of the American Chemical Society, one symposium called “Chemistry and Biological Effects of Maple Food Products” rounded up the latest research on maple’s effect on chronic inflammation.

Maple tree products were found to contain as many as 65 advantageous antioxidants. Researchers suggested that maple food products could aid relieve metabolic syndrome and liver disease, including benefit brain health and help maintain a healthy gut.

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Now, the research carried out by Prof. Seeram and colleagues investigates into the dermatological benefits of maple leaf extract.

The elasticity of the skin is partly due to a protein called elastin. During the aging process, an enzyme called elastase damages elastin, leading to wrinkles.

“We wanted to see whether leaf extracts from red maple trees could block the activity of elastase,” explains Prom Seeram.

Prof. Seeram and his team of researchers focused on compounds in the leaves called glucitol-core-containing gallotannins (GCGs). According to previous studies by the same research group, GCGs can prevent skin inflammation and protect against dark age spots.

The team explored the ability of GCGs to halt the activity of elastase in the lab by carrying out a computational study to determine which GCGs are more effective in blocking elastase.

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The analysis found that GCGs that comprise several galloyl groups blocked elastase more successfully.

A plant-based Botox without injections

The researchers are now eager to transform the botanical extracts of maple leaves into marketable skincare products. Already, they have developed a formula that contains GCGs, which they called “Maplifa.”

They are confident that their products will appeal to customers who want to use natural, plant-based skincare products instead of Botox or other procedures that goes with health risks.

Prof Seeram said;

“You could imagine that these extracts might tighten up human skin like a plant-based Botox, though they would be a topical application, not an injected toxin.”


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